PET-automatic-synthesis-unit for FLT production


PET synthesis of:


The SynChrom FLT system has been developed & designed to produce [F-18]FLT based on nucleophilic substitution. The system is based on the raytest SynChrom R&D system without the hardware which is not required for the FLT synthesis process. raytest is supplying the entire process documentation as well as the responsibility for the successful FLT production on this device.

The SynChrom FLT unit is equipped with one of the unique raytest transparent reactor systems. The entire process is visible. The 500W electrical air heater system & the compressed air cooling enables ultra fast temperature changes in the synthesis reagent solvent. The system monitors the real solvent temperature. Temperature range 20°C - +180°C. SynChrom FLT is equipped with very fast, low hold up volume, solvent resistant and pressure tight (4 bars) magnetic flipper valves. All solvents are transported directly into the reaction vessel without any solvent cross contamination. 

The built-in pressure sensor continuously displays the actual system ( reactor ) pressure. This pressure sensor is also used for automatic gas leakage test after the synthesis unit cleaning procedure. During the process this sensor also observes the process for unexpected “accidents” with selectable warning and shutdown levels. The reactor system is also equipped with a magnetic stirrer mixing system & a tube lifting system.

The unit contains a built-in lead shielding housing for the F-trap as well as a shielded target water collecting vial with radiation detectors for observation, analysis and reporting. (both can be used also without a self owned cyclotron). The target delivery can be done directly to the F-trap or via the target vial.

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