SynChrom FEC

PET-automatic-synthesis-unit for FEC production

Applications

PET synthesis of:

[F-18]FEC

The SynChrom FEC system has been developed & designed to produce [F-18]FLT based on nucleophilic substitution. The system is based on the raytest SynChrom R&D system without the hardware which is not required for the FEC synthesis process. Raytest is supplying the entire process documentation as well as the responsibility for the successful FEC production on this device.

The SynChrom FEC unit is equipped with two of the unique raytest transparent reactor systems. The entire process is visible. The 500W electrical air heater system & the compressed air cooling enables ultra fast temperature changes in the synthesis reagent solvent. The system monitors the real solvent temperature. Temperature range 20°C - +180°C. SynChrom FEC is equipped with very fast, low hold up volume, solvent resistant and pressure tight ( 4 bars ) magnetic flipper valves. All solvents are transported directly into the reaction vessel without any solvent cross contamination.

The built-in pressure sensor continuously displayes the actual system ( reactor ) pressure. This pressure sensor is also used for automatic gas leakage test after the synthesis unit cleaning procedure. During the process this sensor also observes the process for unexpected “accidents” with selectable warning and shutdown levels. The reactor systems are also equipped with magnetic stirrer mixing systems & tube lifting systems.

The unit contains a built-in lead shielding housing for the F-trap as well as a shielded target water collecting vial with radiation detectors for observation, analysis and reporting (both can be used also without a self owned cyclotron). The target delivery can be done directly to the F-trap or via the target vial.

Download link